Vacation home accommodations in Panama
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Top-rated vacation houses in Panama
Guests agree: these vacation houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Panama vacation houses
Family-friendly vacation houses
Vacation home in El Chirú
4.85 out of 5 average rating, 20 reviewsApartment in Buenaventura
Vacation home in La Pintada
4.38 out of 5 average rating, 16 reviewsLa Pintada Inn full hotel for private group
Vacation home in Panamá
Lovely place with exclusive private pool
Vacation home in Juan Gallego
4.84 out of 5 average rating, 81 reviewsPebos Reef, 12 guests, Amazing views!!
Vacation home rentals with a patio
Vacation home in Anton Valley
4.91 out of 5 average rating, 44 reviewsAdorable 2 bedroom home near India Dormida hiking
Vacation home in Volcán
4.82 out of 5 average rating, 33 reviewsBeautiful cabin with balcony
Vacation home in Rio Hato
4.83 out of 5 average rating, 6 reviewsOcean view studio Town Center Playa Blanca Rio Hat
Vacation home in Bocas del Toro
4.58 out of 5 average rating, 40 reviewsPrivate Luxury Over the Water Bungalow
Vacation home in Maria Chiquita
5.0 out of 5 average rating, 23 reviewsPlaya Escondida, Caribe Depa for 8 pax
Vacation home in San Carlos
4.87 out of 5 average rating, 31 reviewsWelcome to our house in Playa Corona
Vacation home in Maria Chiquita
4.95 out of 5 average rating, 21 reviewsPlaya Escondida, Apt with Spectacular Ocean View
Vacation home in San Carlos
5.0 out of 5 average rating, 7 reviewsSpectacular three-bedroom beach friendly
Vacation home rentals with a washer and dryer
Vacation home in Arraiján
4.8 out of 5 average rating, 50 reviewsApartamento En Club De Playa, With Pool and BBQ
Vacation home in Chitré
4.94 out of 5 average rating, 36 reviewsCASA EdditA ° Acogedora casa en Chitré
Vacation home in Maria Chiquita
4.87 out of 5 average rating, 30 reviewsDreamy, Modern Caribbean Home at Playa Escondida
Vacation home in Bocas del Toro Province
4.85 out of 5 average rating, 20 reviewsBeautiful 2 bedroom open air home jungle home
Vacation home in Coronado
4.9 out of 5 average rating, 31 reviewsModern Beach House With Private Beach Access
Vacation home in Maria Chiquita
4.84 out of 5 average rating, 37 reviewsPlaya Escondida apt 200 mt2, 4r 4b waterfront
Vacation home in Bajo Boquete
4.64 out of 5 average rating, 25 reviewsRio Verde: Splendid suite w/ hammock & river view
Vacation home in Playa Blanca Rio Hato
4.72 out of 5 average rating, 29 reviewsComfortable apartment with pool and close to the beach
Destinations to explore
- Loft rentals Panama
- Beach condo rentals Panama
- Bed and breakfasts Panama
- Hotel rentals Panama
- Rentals with beach access Panama
- Monthly Rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Rentals with a patio Panama
- Nature eco lodge rentals Panama
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- Pet-friendly rentals Panama
- Boutique hotel rentals Panama
- Rentals with a firepit Panama
- Cottage rentals Panama
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- Chalet rentals Panama
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- Cabin rentals Panama
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- Rentals with breakfast Panama
- Rentals with an accessible height bed Panama
- Bungalow rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Villa rentals Panama
- Rentals with a home theater Panama
- Fitness-friendly rentals Panama
- Farmstay rentals Panama
- Tiny house rentals Panama
- Rentals with pools Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Family-friendly rentals Panama
- Rentals with lake access Panama
- Island rentals Panama
- Rentals with a fireplace Panama
- Treehouse rentals Panama
- Waterfront rentals Panama
- Boat rentals Panama
- Kid-friendly rentals Panama
- Rentals with a hot tub Panama
- Wheelchair accessible rentals Panama
- House rentals Panama
- Apartment rentals Panama
- Beach house rentals Panama
- Condo rentals Panama
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