Guesthouse vacation rentals in Panama
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Top-rated guesthouses in Panama
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Panama guesthouses
Family-friendly guesthouses
Guesthouse in Nueva Gorgona
4.99 out of 5 average rating, 67 reviewsBeautiful Casita-Paradise in Panama, Nueva Gorgona
Guesthouse in Alto Boquete
4.82 out of 5 average rating, 65 reviewsAccommodation. Sinsonte )
Guesthouse in Jaramillo Arriba
4.92 out of 5 average rating, 37 reviewsCottage Sait
Guesthouse in Bocas del Toro Province
5.0 out of 5 average rating, 4 reviewsLas Palmas Casita at Bluff Beach Retreat
Guesthouse in Boquete
5.0 out of 5 average rating, 9 reviewsVista a Baru
Guesthouse in Panamá
Mochila & Art Family House
Guesthouse in Panamá
4.92 out of 5 average rating, 38 reviewsPrivate cabin and CasaMomote River, Loma Limón.
Guesthouse in PA
4.8 out of 5 average rating, 15 reviewsLa Rosa de Los Vientos, Pedasi, double room
Guesthouses with a patio
Guesthouse in Alto Boquete
4.82 out of 5 average rating, 17 reviewsBungalow Villa Castillo, Boquete.
Guesthouse in Anton Valley
4.83 out of 5 average rating, 18 reviewsCabin The India
Guesthouse in Anton Valley
4.89 out of 5 average rating, 45 reviewsPrivate 1 BR cottage near India Dormida hiking
Guesthouse in Almirante
4.63 out of 5 average rating, 49 reviewsGia's Garage & Home for Bocas travelers
Guesthouse in Almirante
4.84 out of 5 average rating, 25 reviewsEntire guesthouse in Almirante, Bocas
Guesthouse in Rio Sereno
5.0 out of 5 average rating, 3 reviewsThe Farmer’s Shack - Pure Nature
Guesthouse in El Valle de Antón
5.0 out of 5 average rating, 4 reviewsPrivate Suite/Studio 1-Bedroom in Paradise
Guesthouse in Nueva California
5.0 out of 5 average rating, 6 reviewsVolcano View Cottage
Guesthouse rentals with a washer and dryer
Guesthouse in Alto Quiel
4.98 out of 5 average rating, 52 reviewsThe Casita at Finca Philadelphia
Guesthouse in Nueva California
5.0 out of 5 average rating, 13 reviewsVolcan Cloud Forest Escape for two
Guesthouse in Río Hato
4.88 out of 5 average rating, 65 reviewsSustainable Guest house with Pool in Rio Hato
Guesthouse in Boquete
4.67 out of 5 average rating, 9 reviewsCozy Studio Unit with Jawdropping Views!
Guesthouse in Bocas del Toro
4.88 out of 5 average rating, 16 reviewsTiny Studio w/ pool access
Guesthouse in Cambutal
4.83 out of 5 average rating, 6 reviews"La Jungla" Cabaña close to the beach
Guesthouse in Los Naranjos
4.69 out of 5 average rating, 62 reviewsCabaas de Alicia 1
Guesthouse in Boquete District
5.0 out of 5 average rating, 9 reviewsDuplex 1
Destinations to explore
- Loft rentals Panama
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- Family-friendly rentals Panama
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