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Mansion vacation rentals in Panama

Find and book unique mansions on Airbnb

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Popular amenities for Panama mansion rentals

Luxury mansion rentals

Top guest favourite
Apartment in Maria Chiquita
5 out of 5 average rating, 24 reviews

Playa Escondida frente al mar y laguna

RafaelRating, 5 stars1 month ago
Communication was absolutely excellent and the location could not be better. By far the best beach project in Panama. We had a blast.
Guest favourite
Villa in Las Lajas
4.82 out of 5 average rating, 33 reviews

Beach House Where Emy

TylerRating, 5 stars2 months ago
Great place we want to go back already.
Superhost
Home in La Ermita
4.83 out of 5 average rating, 12 reviews

2 beachfront houses, spectacular private beach.

AlexRating, 5 stars2 months ago
good attention, super equipped house that was what we liked the most, beautiful access of Playa and rio super nearby , the stay was wonderful... keep it up.
Guest favourite
Cottage in Panama City
5 out of 5 average rating, 18 reviews

Hacienda La Perezosa in Cerro Azul

TeddyRating, 5 stars1 week ago
Very well maintained and clean. Perfect spot for a relaxing time with ample amenities and service staff. Will definitely repeat!
Superhost
Boat in Río Azúcar
5 out of 5 average rating, 4 reviews

Private Luxury Catamaran

ChrisRating, 5 stars2 months ago
Our catamaran stay in San Blas was incredible! The islands were pristine and beautiful, far from the tourist crowds. The captain was super responsive and knew all the hidden gems, taking us to the best spots. The service and food on board were excellent—fresh, local, and delicious. It was the perfect way to explore the islands in comfort and style. Highly recommend for anyone seeking a unique and unforgettable experience!
Superhost
Home in Coronado
4.75 out of 5 average rating, 24 reviews

CHARMING HOUSE IN FRONT OF THE SEA WITH POOL-CROWNED

MathieuRating, 5 stars1 month ago
I really loved the Hamacas casa What a beautiful place You can’t go wrong being right on the beach Lots of restaurants near by Super safe to walk around Coronado Marcella was super helpful and answered Us every time we had a question The house was great mind you we didn’t really stay in the house other than going to bed Daniel the grounds keeper was super nice and helpful All and all I wouldn’t definitely rent this place again hopefully in a bear future
Top guest favourite
Condo in Maria Chiquita
5 out of 5 average rating, 35 reviews

Playa Escondida. Apartment with ocean views.

IsabelRating, 5 stars1 month ago
We loved the apartment; it was beautiful, fully equipped, immaculate and exactly as shown in the photos. The beds were incredibly soft and comfortable, like sleeping in the clouds, and all bathrooms had hot water. The kitchen was fully equipped and very well arranged. The view from the balcony 10/10. We really love the place. The beach was spectacular. We spent two days there and rent bohios with grill, which allowed us to make the most of the crystal-clear beach and the excellent atmosphere. It was a weekend of a lot of peace and relaxation. We'll definitely be back.
Superhost
Villa in Isla Colon
4.89 out of 5 average rating, 9 reviews

Casa Caracola. Luxury villa. 200 mts from beach

GiyoraRating, 5 stars2 months ago
Our stay at casa Caracola was simply exceptional. It is a spacious, luxurious and perfect for two families. From the moment we arrived, we felt so comfortable that we hardly needed to go anywhere. We spent our days enjoying the beautiful garden and swimming pool, where we had the privilege of seeing toucans, monkeys, and a variety of wild birds. Waking up each morning to the sound of birds singing was an incredible experience. The host, Ricardo, was outstanding. He helped us arrange everything, from private chefs who prepared spectacular meals at the house to booking tours and surf and diving lessons. His attention to detail and willingness to assist made our stay even more special. We also want to highlight Nely, who took care of keeping the house spotless throughout our stay. It was a pleasure to have her help in maintaining everything clean and organized. We will definitely be back. A perfect place for an unforgettable getaway! Thanks Gigi

Pet-friendly mansion rentals

Superhost
Place to stay in Portobelo
4.9 out of 5 average rating, 21 reviews

Oceanfront Villa

AdrianaRating, 5 stars2 months ago
This place is perfect to enjoy a relaxing het away, having the beautiful ocean view and tropical breeze right outside of the house it is priceless! The pool and Jacuzzi are well maiy and make a great complement of the whole experience! The host thought about every detail to make the guests very welcome, by providing essentials for personal cleaning products, kitchen extra essentials and outdoors supplies. We really enjoyed the stay.!
Superhost
Cottage in Panamá Oeste
4.83 out of 5 average rating, 12 reviews

Iwanna Green, Country House with Pool

MonicaRating, 5 stars5 months ago
A totally ecological house with activities for the whole family, a pool surrounded by nature and a theme that makes you want to take out your inner child and have a good time with friends and family while you are surrounded by a cool climate in the bell mountain. Easy access, diversity and neon art in each area of the house, multiple cooking utensils and appliances. .
Guest favourite
Villa in San José
4.84 out of 5 average rating, 64 reviews

The Big Family Mini Resort House @Punta Barco

ItaloRating, 5 stars3 days ago
Excellent experience with the family, our stay was like being at home; the property has everything for adults and children to enjoy. The beach is very close walking, the residential is very exclusive.
Top guest favourite
Home in Nueva Gorgona
5 out of 5 average rating, 21 reviews

Comfortable beach house with pool in Nueva Gorgona

KristoferRating, 5 stars4 weeks ago
Vielka is a wonderful host. She is very responsive and very helpful and accommodating. The home is beautiful and perfect for large groups. I would return again.
Superhost
Cabin in Calobre
4.83 out of 5 average rating, 18 reviews

La Yeguada - Forest Point Cabin

StefanieRating, 5 stars1 month ago
Flexible check-in, variety of kitchen utilities and so on that made the stay very pleasant, everything clean and organized.
Guest favourite
Villa in El Chirú
4.88 out of 5 average rating, 40 reviews

Beach house for families with a pool.

CarlosRating, 5 stars1 week ago
Great outdoor space to relax and enjoy with the family, bbq area was great and plenty of space to chill. Pool was very good and clean! Couple of minutes walk to the beach which was great!
Guest favourite
Villa in Paso Ancho
4.95 out of 5 average rating, 84 reviews

Charming & Enjoyable Cabin surrounded by trees

VivianRating, 5 stars2 weeks ago
A hidden gem in the middle of nature! The cabin was spotless, very comfortable and exactly as shown in the pictures. Our stay in this cabin surrounded by trees was excellent. The place is even more beautiful in person, with spectacular views, clean and cozy spaces, and an atmosphere of total tranquility. Perfect for disconnecting and enjoying with family or friends. The host was very attentive and made sure we made sure we had everything we needed. We would definitely come back! Highly recommended for those looking for peace, fresh air and natural beauty.
Top guest favourite
Villa in Punta Chame
4.97 out of 5 average rating, 120 reviews

Beach House with Pool/Gazebo in Punta Chame!

KarimaRating, 5 stars2 months ago
A great option to spend time with family, relax and above all, feel at home, just what I was looking for and needed. I would go back many more times. It's a house that has everything you could need and more, with many amenities, and the pool is the center of total enjoyment. Polina was very friendly and thoughtful with her attention. Plenty of privacy to enjoy your free time. The nearby beach is very quiet almost at the exit of Chame Bay. Great stay.

Mansion rentals with a pool

Top guest favourite
Home in Panama City
5 out of 5 average rating, 29 reviews

Mountain Retreat

TraciRating, 5 stars3 weeks ago
This home is one of the best and most unique Airbnbs our family has stayed in. The home and grounds were spacious, comfortable, and stunningly beautiful. From the cozy beds to pool and game time with the family, it was exactly what our family needed to relax and get away from our busy lives. The beautiful and friendly orange cat Garfield was an added bonus.
Top guest favourite
Villa in Rio Hato
5 out of 5 average rating, 28 reviews

Villa Agueda Decameron, golf club and swimming pool

JeremyRating, 5 stars3 months ago
What a place, one of the better Air B &B’s in Panama, have everything you require, nice pool, cold jacuzzi that works, very amazing stay Annelise, thanks for everything.
Superhost
Villa in Santa Catalina
4.84 out of 5 average rating, 57 reviews

Infinity Pool Boutique Villa on The Point Break

TimRating, 5 stars3 weeks ago
The accommodation is absolutely brilliant. Lovely rooms, incredible views from the huge terrace and a nice pool. What really stands out it is the hospitality and kindness of our host Pietro: Not only giving us all necessary information and tips on our arrival, he even drove us two times to the supermarket during our stay, as we were a big group and had much stuff to carry. Thank you so much, we had a wonderful stay!
Superhost
Cabin in Chame District
4.72 out of 5 average rating, 29 reviews

A private place for events and parties

ChristianRating, 5 stars3 months ago
The Place is perfect to enjoy with family and friends, it's a very peaceful and beautiful place. Mr. Ahmed is a great person with a good communication and a friendly host. Really worth it!
Guest favourite
Home in Panama City
4.95 out of 5 average rating, 37 reviews

Nice duplex house with a swimming pool.

NapharRating, 5 stars1 week ago
From the moment we arrived, everything was as expected. Gerardo welcomed us upon arrival. He was incredibly responsive and thoughtful, and made check-in a breeze. He took the time to show us the ins and outs of the property, making sure we felt right at home. The space was beautiful and exactly as described—if not better. We were a group of seven (4 adults and 3 teens/pre-teens), and there was more than enough space without feeling like we were on top of each other. The neighborhood was peaceful and conveniently located near a park, supermarket, and restaurants. The pool was clean and well-kept. We would stay here again. Highly recommended to anyone looking for a comfortable and memorable Airbnb experience in Panama!
Top guest favourite
Villa in Boca Chica
5 out of 5 average rating, 13 reviews

On the Beach Villa in Boca Chica!

CoreyRating, 5 stars1 week ago
This place is amazing! Super special location with a beach to surf right outside your back door. Gated community provided great security, we left our car and doors unlocked the whole time with zero concern. Lance and Monty are plugged into the local community and have great recommendations for anything you'd like to do. If you like remote, beautiful locations without tourists buzzing all over then this is the right place.
Superhost
Home in Panamá
4.83 out of 5 average rating, 24 reviews

Spectacular Beach Cabin "Tiny House" San Carlos

IrinaRating, 5 stars2 months ago
Everything as shown in the listing. The place was in perfect condition and very comfortable. The host was very attentive and was always quick to respond to any inquiries. Without a doubt, an excellent option.
Superhost
Villa in San Carlos
4.71 out of 5 average rating, 34 reviews

Casa Helechos, in a beach community with a swimming pool

AngelaRating, 5 starstoday
We loved the house, it is central, close to the super It looks much Better in person than in the photos, super spacious and comfortable, it has all the necessary utensils, the beach is close by. The host's attention is very rewarding, attentive and very friendly.

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