House vacation rentals in Panama
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Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Panama house rentals
House rentals with a pool
Home in Panama
4.96 out of 5 average rating, 142 reviewsVilla Isabella in Coronado Beach Panama
Home in Bocas Del Toro
4.96 out of 5 average rating, 99 reviewsWiona of Villa Paraiso | Beachfront Villa & Pool
Home in Playa Venao
5 out of 5 average rating, 18 reviewsNearly Oceanfront: Blue 3 Bedroom Spacious Villa
Home in Playa Hermosa
5 out of 5 average rating, 27 reviewsEntire house with private pool facing beach !
Home in Río Hato
4.93 out of 5 average rating, 29 reviewsVilla Santorini | Playa Blanca
Home in Bocas del Toro Province
5 out of 5 average rating, 28 reviewsThe Pool House, Beach House on Paunch Beach
Home in Playa Bluff
4.93 out of 5 average rating, 29 reviewsJungle House 100m from the beach
Home in Playa Venao
4.95 out of 5 average rating, 22 reviewsCasa Pelicano - Tropical house w pool and seaview
Weekly house rentals
Home in Altos del Maria
5 out of 5 average rating, 27 reviewsPortazul - A Mountain Retreat
Home in Palenque
4.82 out of 5 average rating, 11 reviewsCaribbean Paradise - Beachfront Getaway
Home in Isla Carenero
4.94 out of 5 average rating, 17 reviewsCasa Blanca-Sea Views/outdoor living/walk to surf
Home in Bastimento
4.85 out of 5 average rating, 47 reviewsBay Of The Floating Palms - Beach Front Home
Home in Nueva Gorgona
5 out of 5 average rating, 7 reviewsSpectacular Beachfront House
Home in Torio
5 out of 5 average rating, 14 reviewsIdeal Creative Retreat Immersed in Forest
Home in Jaramillo
4.93 out of 5 average rating, 14 reviewsCastle in the Sky
Home in La Guaira
4.97 out of 5 average rating, 88 reviewsPuntita Manzanillo, fantastic sea and jungle
Private house rentals
Home in Bajo Boquete
4.99 out of 5 average rating, 68 reviewsBeautiful new house in Boquete
Home in Anton Valley
5 out of 5 average rating, 26 reviewsModern Duplex in El Valle de Anton
Home in Bajo Boquete
4.78 out of 5 average rating, 67 reviews7 sketch mountain Jaramillo house upstairs Boquete
Home in Playa Venao
5 out of 5 average rating, 17 reviewsBeachfront Tropical Chalet Venao with Rancho
Home in Pedasí
4.9 out of 5 average rating, 42 reviewsPedasí :Andromeda Boroda 4-6 p. Beach, swimm. pool
Home in Los Algarrobos
4.96 out of 5 average rating, 24 reviewsLemongrass H. Algarrobos
Home in Santa Fe
4.94 out of 5 average rating, 17 reviewsSanta Fe House with an amazing view
Home in Jaramillo Arriba
5 out of 5 average rating, 14 reviewsHouse in Boquete w/ King Beds, A/C & Hot Tub
Destinations to explore
- Loft rentals Panama
- Smoking-friendly rentals Panama
- Pet-friendly rentals Panama
- Beach condo rentals Panama
- Townhouse rentals Panama
- Rentals with an accessible height bed Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Boutique hotel rentals Panama
- Monthly Rentals Panama
- Rentals with breakfast Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Bed and breakfasts Panama
- Bungalow rentals Panama
- Rentals with beach access Panama
- Rentals with a home theater Panama
- Kid-friendly rentals Panama
- Waterfront rentals Panama
- Hotel rentals Panama
- Rentals with a sauna Panama
- Rentals with a hot tub Panama
- Treehouse rentals Panama
- Beach house rentals Panama
- Island rentals Panama
- Rentals with pools Panama
- Cottage rentals Panama
- Fitness-friendly rentals Panama
- Boat rentals Panama
- Apartment rentals Panama
- Chalet rentals Panama
- Tiny house rentals Panama
- Rentals with lake access Panama
- Rentals with a patio Panama
- Nature eco lodge rentals Panama
- Condo rentals Panama
- Villa rentals Panama
- Rentals with a firepit Panama
- Rentals with a fireplace Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Family-friendly rentals Panama
- Farmstay rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Beach house rentals Panama City
- House rentals Panama City
- House rentals Playa Coronado
- House rentals Altos del Maria
- Yurt Rentals United States
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