Hotel vacation rentals in Upstate South Carolina
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Top-rated hotels in Upstate South Carolina
Guests agree: these hotels are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Upstate South Carolina hotels
Family-friendly hotels
Hotel room in Clemson
5.0 out of 5 average rating, 7 reviewsTwo private rooms with bathroom
Hotel room in Tryon
4.83 out of 5 average rating, 47 reviewsGreenLife Inn at Mimosa Room 208
Boutique hotel in Chimney Rock
4.83 out of 5 average rating, 12 reviewsKing Bedroom - No Cleaning Fees & Free Breakfast!
Hotel in Fletcher
4.86 out of 5 average rating, 56 reviewsCabin 400 sq all for you.
Hotel in Hendersonville
4.67 out of 5 average rating, 6 reviewsLarge King Room, Breakfast & WIFI included
Resort in Scaly Mountain
Spruce Treehouse
Hotel room in Highlands
4.82 out of 5 average rating, 11 reviewsInn at Mill Creek Suite 4 - Satulah
Hotel room in Dillsboro
4.84 out of 5 average rating, 68 reviewsDillsboro Inn Family Suite
Hotels with a pool
Hotel room in Clarkesville
Spacious 2BD/2BA - Blue Ridge Mountains
Hotel room in Lake Lure
4.67 out of 5 average rating, 21 reviewsChimney Rock Inn - Room 4
Hotel in Greenville
5.0 out of 5 average rating, 5 reviewsWingate Greenville Airport (K)
Nature lodge in Mill Spring
5.0 out of 5 average rating, 16 reviewsBright's Creek Lodge - Dbl Queen, ADA, Pet Friend
Resort in Bryson City
5.0 out of 5 average rating, 3 reviewsLodge 06 Pool View
Resort in Lake Lure
4.69 out of 5 average rating, 16 reviewsFairfield Mountains Resort - 2 Bedroom Deluxe
Nature lodge in Bryson City
5.0 out of 5 average rating, 3 reviewsQuaint Airbnb village with gorgeous views!
Hotel in Spartanburg
New place to stayDream House Gatherings
Hotels with a patio
Boutique hotel in Hendersonville
4.8 out of 5 average rating, 10 reviewsDouble Queen Rm: Near DT Hendo & Flat Rock
Hotel in Lake Lure
1 Bedroom Deluxe @ Wyndham Fairfield Mountains
Boutique hotel in Highlands
4.69 out of 5 average rating, 13 reviewsGranite King Room - 1920's Mid Century Lodge
Nature lodge in Franklin
5.0 out of 5 average rating, 7 reviewsThe Lodge at Cat Creek, Appalachian Room
Hotel in Lake Lure
4.67 out of 5 average rating, 3 reviewsApartment suite w private deck within river motel
Hotel in Sapphire
New place to stayFoxhunt at Sapphire Valley Resort 2 Bedroom Unit
Resort in Hendersonville
New place to stayRm 100 Honeymoon Jacuzzi Suite
Hotel in Lake Lure
The Presidential Suite Plus
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