Guesthouse vacation rentals in San Diego
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouses in San Diego
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for San Diego guesthouses
Family-friendly guesthouses
Guesthouse in Encinitas
4.86 out of 5 average rating, 228 reviewsSunset/Ocean View Guest House! Minutes to Beach
Guesthouse in Chula Vista
4.95 out of 5 average rating, 477 reviewsPrivate Casita in Great Eastlake Neighborhood
Guesthouse in San Diego
4.97 out of 5 average rating, 509 reviewsCentral & Serene Secret Garden Guesthouse
Guesthouse in San Diego
4.93 out of 5 average rating, 450 reviewsPrivate Cottage in Walkable North Park w/AC
Guesthouse in San Diego
4.89 out of 5 average rating, 111 reviewsSoCal Tiny Home, Heart of South Park
Guesthouse in San Diego
4.97 out of 5 average rating, 294 reviewsPrivate Guest House with a View
Guesthouse in San Diego
4.84 out of 5 average rating, 318 reviewsPacific Beach Guest House With Garage and A/C
Guesthouse in El Cajon
4.98 out of 5 average rating, 191 reviewsFletcher Hills - modern 1 BR.Easy, no step access.
Guesthouses with a patio
Guesthouse in San Diego
5.0 out of 5 average rating, 110 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
Guesthouse in San Diego
4.98 out of 5 average rating, 102 reviewsStunning Patio! King Bed, Walkable, Games, Parking
Guesthouse in Lakeside
4.94 out of 5 average rating, 103 reviewsSky Mesa-Adorable Cottage on the Hill
Guesthouse in La Mesa
4.98 out of 5 average rating, 252 reviewsLa Mesa Suite
Guesthouse in San Diego
4.99 out of 5 average rating, 152 reviewsAdorable cottage in Talmadge
Guesthouse in San Diego
4.98 out of 5 average rating, 128 reviewsPrivate Studio Cottage with Outdoor Patio
Guesthouse in La Mesa
4.99 out of 5 average rating, 173 reviewsSDCannaBnB #1 *420 *parking *dog-friendly *hot tub
Guesthouse in Oceanside
4.94 out of 5 average rating, 159 reviewsDetached, Private Cottage! Fenced, PET friendly!
Guesthouse rentals with a washer and dryer
Guesthouse in San Diego
4.87 out of 5 average rating, 420 reviewsThe Golden Hill mosaic "casita"
Guesthouse in San Diego
4.95 out of 5 average rating, 111 reviewsRelax in a Centrally Located, Modern Guest House
Guesthouse in San Diego
4.98 out of 5 average rating, 118 reviewsCasita Hermosa - Close to everything in San Diego
Guesthouse in San Diego
4.94 out of 5 average rating, 105 reviewsAdorable studio/self check-in & off street parking
Guesthouse in San Diego
4.92 out of 5 average rating, 529 reviewsThe Best Cottage in North Park!
Guesthouse in San Diego
4.99 out of 5 average rating, 133 reviewsCarrie’s North Park Casita, in Heart of San Diego
Guesthouse in San Diego
4.95 out of 5 average rating, 296 reviews*BEAUTIFUL* Sunny Home in Golden Hill
Guesthouse in San Diego
4.95 out of 5 average rating, 117 reviews1BR Casita in the Heart of Kensington!
Quick stats about guesthouse rentals in San Diego
Total rentals
980 properties
Rentals with dedicated workspaces
530 properties have a dedicated workspace
Rentals with a pool
90 properties have a pool
Pet-friendly rentals
240 properties allow pets
Family-friendly rentals
140 properties are a good fit for families
Total number of reviews
101K reviews
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