Guesthouse vacation rentals in South America
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouses in South America
Guests agree: these guesthouses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for South America guesthouses
Family-friendly guesthouses
Guesthouse in Santa Teresa
4.81 out of 5 average rating, 254 reviewsGarden Studio - Home away from Home
Guesthouse in Amparo
4.91 out of 5 average rating, 191 reviewsCasa do Lago no Circuito das Aguas em Amparo
Guesthouse in Playa Hermosa
4.91 out of 5 average rating, 338 reviewsLa Casita by Lina
Guesthouse in Florianópolis
4.93 out of 5 average rating, 214 reviewsFoot in Beach 1, steps from campeche beach!
Guesthouse in Playa Hermosa
4.96 out of 5 average rating, 214 reviewsCozy Guesthouse 5 mins To Beach
Guesthouse in Ipojuca
4.83 out of 5 average rating, 319 reviewsSuite in the center with privacy
Guesthouse in Portao de Ferro 2
4.85 out of 5 average rating, 291 reviewsStudio Cozy in Paraty
Guesthouse in Alpes de Atibaia
5 out of 5 average rating, 295 reviewsCozy Edicula in a family setting
Guesthouses with a patio
Guesthouse in Japaratinga
5 out of 5 average rating, 9 reviewsSuite with sea front kitchen
Guesthouse in San Carlos de Bariloche
4.98 out of 5 average rating, 52 reviewsCozy studio on the lake shore
Guesthouse in Florianópolis
4.97 out of 5 average rating, 31 reviewsLoft na Praia Mole
Guesthouse in El Calafate
4.94 out of 5 average rating, 139 reviewsCozi guest house in a beautiful garden
Guesthouse in Nosara
5 out of 5 average rating, 36 reviewsPura Vida Magic-Studio Bliss (single occupancy)
Guesthouse in Village de Búzios
4.9 out of 5 average rating, 101 reviewsTwo Bedroom Bungalow with Amazing Views
Guesthouse in Orosi
4.95 out of 5 average rating, 212 reviewsJungle Jacuzzi & Chimney-Casa Verde
Guesthouse in Luján de Cuyo
4.98 out of 5 average rating, 115 reviewsPistacho Eco Lodge Wine Route. Romantic Cabin
Guesthouse rentals with a washer and dryer
Guesthouse in Monte Verde
4.99 out of 5 average rating, 161 reviewsRomantic bungalow, memorable days in Monte Verde
Guesthouse in Paraty
4.92 out of 5 average rating, 165 reviewsSummer house Missanga
Guesthouse in Puerto Varas
4.92 out of 5 average rating, 154 reviewsTiny Home Playa Hermosa Lake Llanquihue
Guesthouse in Jardim Paulista
4.99 out of 5 average rating, 323 reviewsLivia Chalet! Rustic chalet surrounded by gardens
Guesthouse in Tamarindo
4.97 out of 5 average rating, 205 reviewsPool side Deluxe Cottage
Guesthouse in Vila Madalena
4.96 out of 5 average rating, 135 reviewsPleasant space in green area in V. Madalena
Guesthouse in Vila Gilda
4.88 out of 5 average rating, 204 reviewsCASA Completa prox centro Sto André (Entire use)
Guesthouse in Viña del Mar
4.85 out of 5 average rating, 503 reviewsDepartamento Independiente in Cerro Esperanza
Destinations to explore
- Monthly Rentals South America
- Shipping container rentals South America
- Rentals with an accessible height bed South America
- Cabin rentals South America
- Rentals with a sauna South America
- Townhouse rentals South America
- Vacation home rentals South America
- Rentals with a kayak South America
- Tipi rentals South America
- House rentals South America
- Tiny house rentals South America
- Cave rentals South America
- Ski-in/ski-out rentals South America
- Rentals with an accessible height toilet South America
- Houseboat rentals South America
- Fitness-friendly rentals South America
- Island rentals South America
- Rentals with lake access South America
- RV rentals South America
- Yurt rentals South America
- Cottage rentals South America
- Smoking-friendly rentals South America
- Boutique hotel rentals South America
- Entire floor rentals South America
- Treehouse rentals South America
- Loft rentals South America
- Rentals with a home theater South America
- Hotel rentals South America
- Nature eco lodge rentals South America
- Rentals with breakfast South America
- Rentals with an EV charger South America
- Private suite rentals South America
- Rentals with outdoor seating South America
- Waterfront rentals South America
- Bed and breakfasts South America
- Earth house rentals South America
- Rentals with a hot tub South America
- Tent rentals South America
- Beachfront rentals South America
- Rentals with a washer and dryer South America
- Rentals with beach access South America
- Rentals with a patio South America
- Chalet rentals South America
- Serviced apartment rentals South America
- Luxury rentals South America
- Dome rentals South America
- Farmstay rentals South America
- Bungalow rentals South America
- Boat rentals South America
- Pet-friendly rentals South America
- Kid-friendly rentals South America
- Condo rentals South America
- Campsite rentals South America
- Resort rentals South America
- Rentals with a firepit South America
- Apartment rentals South America
- Villa rentals South America
- Rentals with pools South America
- Ranch rentals South America
- Aparthotel rentals South America
- Family-friendly rentals South America
- Rentals with a balcony South America
- Hostel rentals South America
- Rentals with a fireplace South America
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom