Vacation rentals in Santa Isabel District

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Top-rated vacation rentals in Santa Isabel District

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Superhost

Cottage in Palenque

4.88 out of 5 average rating, 81 reviews

Beachfront House in Caribbean sandy beach

OlgaRating, 5 stars1 month ago

We stayed in the house in February , and while the house itself was very basic, the location made it a special experience. the view and the sound of the waves were unbeatable. The road in dry season was ok, just the last 7km were not that good but totally manageable. The house is simple, but given how remote and undeveloped the area is, we weren’t expecting much in terms of amenities. The beach directly in front of the house isn’t ideal for swimming as the waves were too rough, but just a 10-minute walk to the left if you face the ocean, we found a beautiful lagoon protected by the reef, perfect for a swim. One big plus was that we didn’t have mosquito issues since it was February and quite windy. Overall, my family loved the experience, and Francisco was very helpful throughout our stay. There’s not much to do here but If you’re looking for a peaceful getaway close to nature, this place is a great option!

Superhost

Home in Palenque

4.81 out of 5 average rating, 21 reviews

Caribbean Paradise - Beachfront Getaway

KristinRating, 5 stars1 month ago

The house is very comfortable, very spacious, has everything you need and more. It has a cute beach, the great pool, spacious patio for the pets who were happy. In general the house has a lot of good things, something that helped us a lot, was that one of the days due to things of nature there were jelly in the sea and we could not get in, but since the house has a pool we were happy all day in the pool, we saw the nearby houses without a pool the neighbors could not get into the sea and they had no pool, so that's an important plus of the house and the other excellent thing is Sugey and Alejandro, the caretakers of the house, not only kept the house clean but went out of their way to help us with my sister who had a flat tire several minutes away from the house, they were always very attentive to us. It was my birthday weekend and it was perfect! We will definitely be back!!!

Guest favourite

Apartment in Juan Gallego

4.85 out of 5 average rating, 112 reviews

Pebos Reef, apt #2, Amazing views !!

NicholasRating, 5 stars3 weeks ago

I cant say enough positive things about this place and the host. Very flexible with check-in and the location was AMAZING! Right on the water. Accomodarions were excellent! Very clear, everything functional. Daniel was very prompt with a response if I had any questions. He even helped connect us with someone who got us a small boat tour and rook us to some of the nearby islands and sights. My brother and I spent a full day exploring and enjoying the local food and beaches. Even the common areas here were very comfortable and the views spectacular. Will definitely be coming bakc the next time I'm in Panama! Thank you to David and our local on-site helper Jesus for making this one of the highlights of our trip to Panama.😁

Guest favourite

Home in Viento Frío

5 out of 5 average rating, 7 reviews

Casa Canalú

LeticiaRating, 5 stars3 months ago

The place where the accommodation is located is privileged, within a very small village. You have to stay in the house, which has its own beach because there is nothing to do or know about in the area. The owner also offers some boat rides to do with one of the caretakers. The house is very well equipped, you have to keep in mind that the space to eat, table and chairs is open and when it rains hard and with a breeze everything gets wet. Also consider that there is no WiFi (although we had a temporary solution that worked half way as Federico supports us with that order). Also only 1 of the 4 bathrooms has hot water, the 2nd did not work. But otherwise, everything is perfect, the aquatic implements are the maximum to enjoy the sea, it is a private pool, with exit to a river space between mangroves. Federico was pending and available long before check in. Very helpful and kind. Definitely nice space to share with several families

Villa in Palenque

5 out of 5 average rating, 9 reviews

Beach Front House Surrounded by 2 Private Beaches

DeniseRating, 5 stars9 months ago

We had a wonderful stay. I like the the fact that the kitchen is well equipped with good appliances and enough plates and glasses. Yudi and Carlos were great in making sure all our needs were met. Leticia, our host, provided enough drinking water and ice. We appreciated that. It's a great place for families. Our children loved the snorkeling. A piece of paradise in Panama!

Home in Palenque

5 out of 5 average rating, 8 reviews

Beach Front Caribbean Paradise at Palenque

EillenRating, 5 stars50 months ago

Simply unmatched, the place is magical! The house is steps away from the crystal clear beach, clean and calm like a pool with spectacular sunsets. We loved being able to do Kayat, paddle and play with our kids in the yard surrounding the house which is huge and the lawn is too cute, looks like a rug. The house is very cozy, no sound enters through the windows as they are thick and the air conditioners are new. There is a team of employees available to help clean and as much as one wants to include going down fresh coconut from the palms to drink pipe water. The host was always on the lookout and I make sure we were comfortable from the moment we booked until check out. We want to come back, thank you very much for this amazing experience.

Superhost

Home in Cuango

4.71 out of 5 average rating, 7 reviews

Beach house in Colón, Panama

AndreinaRating, 5 stars1 month ago

The place is very cozy, it has everything you need to have a quiet trip and without much noise more than the sound of the sea It is perfect for going with dogs as it has a large garden and with walls for them to run The rooms and the super service. We were able to get quite a rest away from everyday life and get to know something new Thank you

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Popular amenities for Santa Isabel District vacation rentals

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Other great vacation rentals in Santa Isabel District

Hotel room in Santa Isabel District

4.5 out of 5 average rating, 6 reviews

Hotel Macolla Beach

FrixilaRating, 5 stars22 months ago

Excellent paradise place, I recommend it. Very good service, friendly people, variety of entertainment, excellent restaurant, they have very good chefs , the manager of excellent.

Private room in Palenque

3.67 out of 5 average rating, 3 reviews

Hostal Casa Blanca

NitziaRating, 5 stars4 months ago

a nice place, away with peace around

Guest favourite

Apartment in Juan Gallego

4.86 out of 5 average rating, 183 reviews

Pebos Reef, apt #1, Amazing location !

Ana IsabelRating, 5 stars1 month ago

An unforgettable family experience. The place captivated us, the beach, with its natural pools and reefs. It was perfect to enjoy the surroundings and the comfort of the apartment. Ideal to relax and enjoy with family. Thanks Daniel and Jesus for all the attention, you're the best. We will certainly return.

Guest favourite

Private room in Garrote

4.78 out of 5 average rating, 9 reviews

Sailboat with beach access in Colón

淼Rating, 5 stars1 month ago

Spending the night on the boat was a unique and serene experience. Falling asleep to the gentle sea breeze and the sound of the waves was a perfect escape from the noise of the city. The boat was well-equipped, the kitchen was compact but functional, and the host provided plenty of ingredients, making us feel at home. The entire trip was well-organized, and the host’s hospitality made the experience even more special. They had two lovely guys who added a lot of joy to the trip. If you’re looking for a getaway to disconnect from the world and immerse yourself in nature, this is the perfect choice! Highly recommended! ⭐⭐⭐⭐⭐

Private room in Portobelo

4.92 out of 5 average rating, 12 reviews

Finca Doña Toña

CapeicRating, 5 stars48 months ago

Ivan was really nice and attentive to us. The photos don't do the place justice. The atmosphere is very relaxed, good music, and they will fall in love with Ellie and Napoleon!

Private room in Puerto Lindo

4.52 out of 5 average rating, 66 reviews

Hostel Wunderbar Palm Room

FaeRating, 5 stars10 months ago

We have stayed at Hostal Wunderbar several times. Peter and Sylvia are always very helpful. The hostal is within walking distance of Puerto Lindo and Linton Bay Marina.

Superhost