
House vacation rentals in Brookline
Find and book unique houses on Airbnb
Top-rated house rentals in Brookline
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for Brookline house rentals
House rentals with a pool

Luxury Ultra Modern House in Newton ; Boston
Excellent location! Great stay for a family away from home! House was magnificent and modern. Beautiful upstairs with an open layout and a downstairs living room. Plenty of space to relax and enjoy each other’s company. Close to the Newton center to access the (T)rain so Boston is easily accessible. Great communication with Amir! He responded quickly with any questions I had! Would definitely come back for another family vacation!

Villa with private Pool in Boston's Elite Enclave
We had a great family vacation in Serge's beautiful house. A quiet, peaceful neighborhood, everything looked exactly like in the pictures. Everything was clean, Serge's instructions were spot on, and his helpful attitude was unmatched by any Airbnb host I've dealt with in the past. Always proactive, reaching out to make sure we didn't need anything else. Any request was immediately responded to and addressed. We hope to return here in the future, it was really great!

Large Pool, Nature Trails, Redd's Pond, 4-Bed
We had a great stay in Marblehead. We love the area and the cute shops and restaurants. Amy was an amazing host. Always responsive, very friendly and super helpful and accommodating. The property was very clean and comfortable! I would highly recommend booking a stay with Amy as your host. I can’t say enough good things about her attentiveness and help. Her communication with us was very helpful and made the whole experience effortless.

Beautiful Spacious 4BRM House!
We have been using short-term rentals as a family since 2011. This is by far the best appointed house we've ever stayed in. Plenty of everything -- basic groceries, towels, dishes, parking, beds and baths. It's a classic New England home with thoughtful updates. Love the vintage touches! Everything was first rate and we were comfortable for our short visit. We will be back!

the house of id; vintage shop, accessible space
This place is a VIBE!!! And I am so happy that this place was the exact vibe I was looking for to record my in person podcast. My guests were blown away, my social media was on fire and I am sure my content will be too once it's ready. Thanks Dara & Paige for opening your home so I can bring my dream project to life.

Spacious vacation unit in premium suburban town
Scott’s apartment is fantastic! It is located on the lower floor of his house. It is very open and light. The bedrooms are spacious and the mattresses extremely comfortable. The kitchen and living area is also spacious, with beautiful views of the woods. There is everything you need for a comfortable stay. The bathrooms are also very well equipped, with very nice towels. There is a washer and dryer, as well as an ironing board and iron. The heating system worked superbly during our stay. We were in the area to visit with family and friends, and the house is located in a perfect location, whether you need drive north or south, east or west! We look forward to staying at Scott's house in the future. Comunication with Scott was very easy and he checked in to see how we were doing. Thank you, Scott, for a lovely stay! We will be back.

Spacious 3-BR Furnished Beach Home
We had a wonderful stay. Perfect place for families with children. So close to the beach with all the beach and home necessities you need while on vacation! Quaint town that was quiet but still has plenty of restaurants to visit. Overall, a great place!

Hidden Gem near Boston w/ Private lake access
The property was stunning and impeccably clean, matching the description perfectly. We had a wonderful time and enjoyed the convenient location with a trail to see horses and access to the lake. The host was incredibly accommodating, and we are looking forward to returning with our family. One suggestion for improvement would be to provide garage access to the house for elderly guests who may have difficulty with stairs, as the pathway, although beautiful, was quite lengthy for my elderly parents. Nonetheless, we all had a fantastic time. Thank you.
Weekly house rentals

Entire House Near South Shore Hospital/Whole Foods
My groups stayed at Trang’s home for 2 night and our stay was perfect. The home was exactly as pictured in the listing and was very clean and spacious. Check-in instructions were straight forward and easy to understand. Would definitely stay again in the future if we ever find ourselves in the area.

Charming South End Farmhouse - Near Northeastern!
We had a great time on a New England road trip! We loved the restaurant MIDA went twice! Wine and liquor store is also close by.

Tewksbury, MA --5 night minimum stay--4 beds, 2.5 baths, quiet street, 5 min drive to shops
Lauren’s house was the perfect place to stay for Christmas. It had everything we could possibly need and the garage was so convenient. I appreciated the night lights throughout the house. I felt very much at home and would highly recommend staying at Lauren’s!

Mid-Century Modern in Historic Lexington
Samuel's place is truly beautiful! What a setting in the woods! Everything was great.

Private suite 1 BR, 1 BA, 1 LR, 1FLR
I had a great stay with Q&A. The apartment was clean and cosy and had all I needed; it is situated at the lower garden level at the back of the house with a lovely view and even a small terrace. Q&A are such great hosts! Very friendly and super quick in their communication, and very attentive to my needs. I could use one of their bicycles to go to the venue where my conference was, and they also gave me a late check-out. I felt very welcome and will definitely be back!

Large 4Bed 2Bath Clean Alternative to Hotel Living
Great place to stay, highly recommended!

Heights House - 93 Walkscore|Halloween|Grill
Darryl was more than helpful, and he had amazing recommendations. We stay at a lot of places, and this one was more than what I expected. We enjoyed our time and he allowed for me to not worry as much when leaving the pup even just for dinner. It’s nice to find pet friendly places, especially when I’m constantly worrying. I would recommend to anyone with well behaved pups and anyone for that matter. The coffee bar, the backyard, location was in a quiet and beautiful neighborhood, just minutes from downtown. It’s well worth the walk and the scenery, even in 40 degree temps. We would stay every other month if could be.

2BR—Charming 1900s Home—1st Floor—25min to Boston
Amazing price and amazing place to spend Halloween! Great places to eat and adventure around! The house was peaceful but had very friendly atmosphere with the neighbors. If I could have Andrea be the host for every air bnb I would be greatful knowing I have someone that's reliable and great with communication. She will treat you right and has great recommendations!
Private house rentals

New Single Family with 5B3B
Everything was perfect! House was beautiful! I would definitely stay here again

Large House, Ocean Views, 2 Kitchens/Dining Rooms
I booked this beautiful Swampscott home for my wife's 30th birthday and we couldn't have been more pleased. The house, views, and location were incredible. My wife, family, and friends couldn't stop raving about the Air BnB selection and we had the best time. The cherry on top was an amazing local restaurant at the bottom of the hill which we enjoyed almost every night. 10/10 would recommend to anyone interested in this rental. Ryan was a great host and made everything easy!

Charming Home in Reading with a Large Yard
I recently stayed at Peter's place, and it was exactly as described in the posting. The pictures were accurate, and I was pleased to find the space clean and well-maintained upon arrival. The location is fantastic, as I grew up in the area. I truly couldn't have asked for a better experience. I wouldn’t hesitate to book again in the future. Highly recommend!

Residential home with free parking
Great space. There were 8 of us that stayed. We mainly were out in about during the day going to Boston breweries. We didn't spend a lot of time there, but we hung out there in the evenings. Bill hooked us up with a bag of charcoal for the grill so we could cook up some steaks. The house has a great backyard area. The kitchen and dining room area was big enough to accommodate us. Beds were comfy and bathrooms were clean. Great shower heads. Off street parking was great for both our vehicles.

The House by the Sea
This was the PERFECT place for my family’s girls trip to Salem. It was only a 12 minute drive into town. The house is breathtaking!!! The pictures do not do it any justice. Everything is spotless and very welcoming. The private beach is a 3 minute walk up the road. The neighborhood is very peaceful and the neighbors were also very friendly. Tracy was an amazing host!!! 10/10 recommendation.

5 BR single House near beach 15 mins to boston
The house is spacious and very comfortable, ideal for large groups, everything was clean and organized. The house has everything you need for a long stay, well-equipped kitchen and bathrooms. The neighborhood is quiet and safe, close to the center and public transportation, supermarkets, etc. Ben is super friendly and communicates quickly. I recommend 100% this stay we had a great time.

Beautiful home away from home!
Mark and Suzanne's home is what we needed on our trip to Peabody. It is clean and the kitchen is well equipped. It is in a quiet cul de sac and the backyard is beautiful. Won't mind staying here again next time we are back in Peabody.

Luxury Brookline/Boston 6 bedroom
Loved the 'character' of the home. It was built in the 1800's so had that old school charm, wonderful craftsmanship but has the necessary updates as well (bathrooms, kitchen and living spaces). We couldn't get over how cool the neighborhood is...tons of beautiful homes that were built in the late 1800s/early 1900s. In fact, JFKs birthplace (first home) was about 2 blocks away. It is now a national park and free to tour. Great bakeries at the end of the street. We were there to tour Boston/historical sites and I was surprised how close everything was. Nicole was super responsive and wonderful to work with.
Quick stats about house rentals in Brookline
Total rentals
200 properties
Nightly prices starting at
$43 CAD before taxes and fees
Total number of reviews
8.4K reviews
Family-friendly rentals
70 properties are a good fit for families
Pet-friendly rentals
30 properties allow pets
Rentals with dedicated workspaces
120 properties have a dedicated workspace
Destinations to explore
- Boston Vacation rentals
- Cape Cod Vacation rentals
- The Hamptons Vacation rentals
- Hudson Valley Vacation rentals
- Long Island Vacation rentals
- Plainview Vacation rentals
- East River Vacation rentals
- New York Vacation rentals
- Jersey Shore Vacation rentals
- Pocono Mountains Vacation rentals
- Montreal Vacation rentals
- Philadelphia Vacation rentals
- Rentals with a firepit Brookline
- Bed and breakfasts Brookline
- Condo rentals Brookline
- Rentals with outdoor seating Brookline
- Rentals with a fireplace Brookline
- Rentals with an EV charger Brookline
- Rentals with breakfast Brookline
- Fitness-friendly rentals Brookline
- Apartment rentals Brookline
- Loft rentals Brookline
- Rentals with a washer and dryer Brookline
- Kid-friendly rentals Brookline
- Pet-friendly rentals Brookline
- Rentals with pools Brookline
- Rentals with a patio Brookline
- Family-friendly rentals Brookline
- Private suite rentals Brookline
- Rentals with a hot tub Brookline
- House rentals Norfolk County
- House rentals Massachusetts
- House rentals United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Hampton Beach
- Boston Common
- TD Garden
- Fenway Park
- North Hampton Beach
- Harvard University
- Brown University
- Onset Beach
- Sagamore Beach
- New England Aquarium
- Faneuil Hall Marketplace
- Scusset Beach
- Goddard Memorial State Park
- Prudential Center
- Symphony Hall
- Isabella Stewart Gardner Museum
- Oakland Beach
- Phillips Beach
- Museum of Fine Arts, Boston
- Pinehills Golf Club
- Hampton Beach State Park
- Roger Williams Park Zoo
- Sandy Point Beach
- Cranston Country Club