Villa vacation rentals in James Island
Find and book unique villas on Airbnb
Top-rated villa rentals in James Island
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you.
Popular amenities for James Island villa rentals
Private villa rentals
Villa in Kiawah Island
4.96 out of 5 average rating, 98 reviewsSpacious new 2BR Villa across beach near Sanctuary
Villa in Seabrook Island
4.84 out of 5 average rating, 63 reviewsPrivate island villa with luxury resort amenities!
Villa in Seabrook Island
4.93 out of 5 average rating, 58 reviewsNewly Remodeled Villa, 5 Minute Walk to Beach
Villa in Seabrook Island
4.87 out of 5 average rating, 38 reviewsSeabrook Golf View Villa: Pickleball, Bike & Pool
Villa in Kiawah Island
4.93 out of 5 average rating, 99 reviewsClean & Comfortable! Steps to the beach!
Villa in Seabrook Island
4.91 out of 5 average rating, 35 reviewsUpscale Villa, Amenity Included! Dog Friendly
Villa in Seabrook Island
4.87 out of 5 average rating, 55 reviews711 Spinnaker centrally located to EVERYTHING!
Villa in Johns Island
4.73 out of 5 average rating, 11 reviewsBeach and Golf Paradise | Vaughan Villa
Luxury villa rentals
Villa in Isle of Palms
4.96 out of 5 average rating, 55 reviewsLuxury Isle of Palms Home Steps to Beach with Pool
Villa in Kiawah Island
5.0 out of 5 average rating, 27 reviewsOcean Front! Beach is steps away. Clean and Crisp!
Villa in Seabrook Island
4.93 out of 5 average rating, 14 reviewsLuxury Seabrook Isl Beach Condo
Villa in Seabrook Island
Seaside Therapy - An iTrip Vacations Home
Villa in Kiawah Island
4.94 out of 5 average rating, 17 reviewsOceanfront Windswept Villa
Villa in Isle of Palms
4.79 out of 5 average rating, 29 reviewsBeachfront IOP Villa with Outdoor Pool. Remodeled!
Villa in Johns Island
5.0 out of 5 average rating, 4 reviews3 Bedroom 2 Bath Duneloft Villa! Neighborhood Pool
Villa in Isle of Palms
5.0 out of 5 average rating, 5 reviewsOceanfront Villa in Wild Dunes! Community Pool!
Villa rentals with a pool
Villa in Isle of Palms
4.77 out of 5 average rating, 47 reviewsUpdated 2BR | Balcony | Pool | Dock
Villa in Isle Of Palms
4.78 out of 5 average rating, 40 reviews7C Seagrove - Sweetgrass
Villa in Seabrook Island
4.67 out of 5 average rating, 3 reviewsA+ Coastal Escape - Club Access
Villa in Seabrook Island
4.96 out of 5 average rating, 24 reviewsUpscale, Private,Breathtaking Views
Villa in Seabrook Island
Courtside Dream | Private Condo | Amazing Sunsets
Villa in Johns Island
4.73 out of 5 average rating, 26 reviewsDog friendly villa on 8th hole of golf course
Villa in Isle of Palms
4.92 out of 5 average rating, 13 reviewsPort O' Call B103 - Oceanfront Oasis! Walkout!
Villa in Isle of Palms
5.0 out of 5 average rating, 7 reviewsPort O' Call F102 - Oceanfront Oasis w/ Walkout!
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